An analysis of deaths involving COVID-19 that occurred between 2 January and 2 July 2021 in England, by vaccination status. It’s a detailed analysis of deaths involving COVID-19 that occurred in fully vaccinated individuals, published by UK Office for National Statistics.
Here are the main points of the analysis:
- In England, between 2 January and 2 July 2021, there were 640 deaths occurred in people who were fully vaccinated, which includes people who had been infected before they were vaccinated.
- The risk of death involving COVID-19 was consistently lower for people who had received two vaccinations compared to one or no vaccination.
- “Breakthrough cases” are where infection has occurred in someone who is fully vaccinated, whereas we define a “breakthrough death” as a death involving COVID-19 that occurred in someone who had received both vaccine doses and had a first positive PCR test at least 14 days after the second vaccination dose; in total, there were 256 breakthrough deaths between 2 January and 2 July 2021.
- 13.1% of breakthrough deaths occurred in people who were identified as likely to be immunocompromised from hospital episodes or causes of death, compared to 5.4% for other COVID-19 deaths.
Deaths involving COVID-19 by vaccination status
The risk of a new infection following vaccination is highest during the first 21 days after the first vaccination, as shown by analysis of the COVID-19 Infections Survey.
There were 458 deaths involving COVID-19 in people who received their second dose at least 21 days before the date of death.
Table: There were 640 deaths involving COVID-19 of people who had received both vaccination doses
|Vaccination status||Deaths involving|
as percent of
|All deaths regardless of vaccination status||51,281||214,701||19.3|
|Deaths within 21 days of first dose||4,388||14,265||23.5|
|Deaths 21 days or more after first dose||7,289||66,533||9.9|
|Deaths within 21 days of second dose||182||11,470||1.6|
|Deaths 21 days or more after second dose||458||57,263||0.8|
Source: Office for National Statistics – National Immunisation Management Service, NHS Test and Trace
Characteristics of breakthrough deaths
The linked data includes 252 breakthrough deaths and 43,956 total deaths involving COVID-19, 98.4% and 85.7% respectively of all breakthrough and total deaths involving COVID-19 that occurred between 2 January and 2 July 2021.
|Male||154 (61.1%)||22,819 (52.2%)||89,498 (48.5%)|
|Female||98 (38.9%)||20,885 (47.8%)||94,901 (51.5%)|
|193 (76.6%)||32,567 (74.5%)||128,454 (69.7%)|
|59 (23.4%)||11,137 (25.5%)||55,945 (30.3%)|
|Limited a lot by|
problem or disability
|80 (31.7%)||12,152 (27.8%)||44,642 (24.2%)|
|Limited a little by|
problem or disability
|80 (31.7%)||12,604 (28.8%)||50,817 (27.6%)|
|Not limited by|
problem or disability
|92 (36.5%)||18,948 (43.4%)||88,940 (48.2%)|
|Immunocompromised||33 (13.1%)||2,360 (5.4%)||18,049 (9.8%)|
|219 (86.9%)||41,344 (94.6%)||166,350 (90.2%)|
Source: Office for National Statistics – Public Health Data Asset, National Immunisation Management Service, NHS Test and Trace
- The median age for breakthrough deaths was 84 and 61.1% of the deaths occurred in males, despite there being more elderly women than men, and therefore initially more fully vaccinated women who could experience a breakthrough death. For all other deaths involving COVID-19 occurring between 2 January and 2 July 2021 in the PHDA dataset, the median age was 82 and 52.2% were male.
- 13.1% of the breakthrough deaths occurred in people who were immunocompromised, compared to 5.4% for other deaths involving COVID-19.
- A greater proportion of breakthrough deaths occurred in those who were clinically extremely vulnerable (76.6%, 193 deaths), than other COVID-19 deaths (74.5%, 32,567 deaths) or non-COVID-19 deaths (69.7%, 128,454 deaths).
- A similar trend is observed for disability and long-term health problem status, with proportions of deaths among people self-reporting that they are “limited a lot” on the 2011 Census as 31.7%, 27.8% and 24.2% for breakthrough deaths, other deaths involving COVID-19 and non-COVID-19 deaths respectively.
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